Anti-Cancerous and Anti-Tumor Research Papers

 

This study shows that annonaceous acetogenins present in soursop stops cell growth for cancerous cells and it is also equally effective on drug resistant cancer cells. Tumor cell growth inhibition by several Annonaceous acetogenins in an in vitro disk diffusion assay

This study shows the effect of soursop fruit extract on human breast cancer cells and it shows that the growth of the cells is inhibited. Selective growth inhibition of human breast cancer cells by graviola fruit extract in vitro and in vivo involving downregulation of EGFR expression

The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells.This study shows that bullatacin, an acetogenin of soursop, reduces cellular energy and is toxic to multidrug-resistant cancer cells.

Pancreatic tumors become resistant to conventional chemotherapies. This study shows that graviola or soursop extract killed pancreatic cancer cells by blocking their access to the energy source ATP.View this paper

Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism

Annonacin induces cell cycle-dependent growth arrest and apoptosis in estrogen receptor- _-related pathways in MCF-7 cells

Breast cancer cells commonly become resistant to Tamoxifen. This study shows that annonacin(which in present in soursop) stopped cancer cells' growth and reduced tumor size at 7-22 days. View this paper
Chemopreventive Potential of Annona Muricata L Leaves on Chemically-Induced Skin Papillomagenesis in Mice

This study shows that the extract of soursop leaves was able to suppress tumor before it started growing as well as growth of the tumor even at lower dosage. View this paper
Selective Action of Acetogenin Mitochondrial Complex I Inhibitors

This is a study on the acetogenins from various plants. Acetogenin from soursop proved to be toxic to selective bad cells and a panel of tumor cell lines including multidrug- resistant cells. View this paper
Quantitative Assessment of the Relative Antineoplastic Potential of the n-butanolic Leaf Extract of Annona Muricata Linn. in Normal and Immortalized Human Cell Lines View this paper

Quantitative Assessment of the Relative Antineoplastic Potential of the n-butanolic Leaf Extract of Annona Muricata Linn. in Normal and Immortalized Human Cell Lines

ANTI-DEPRESSION PROPERTIES

Isoquinoline derivatives isolated from the fruit of Annona muricata as 5-HTergic 5-HT1A receptor agonists in rats: unexploited antidepressive (lead) products

This study shows the effect of isoquinoline, a compound present in the fruit soursop on rats and it shows an antidrepressive effect

FOR HERPES SIMPLEX VIRUS

Effect of the extract of Annona muricata and Petunia nyctaginiflora on Herpes simplex virus

This study shows the effect o extract of Annona muricata on Herpes Simplex virus.

ANTI-DIABETIC PROPERTIES

This study shows that leaf extracts of soursop have anti-diabetic properties as it helps in reducing blood glucose level. View this paper

Anti Hyperglycemic Activities of Annona Muricata (Linn)

HYPOTENSIVE PROPERTIES


This study shows that leaves of the soursop caused significant reduction in blood pressure with only a slight affect on heart rates.

Possible mechanisms of action of the hypotensive effect of Annona muricata (soursop) in normotensive Sprague–Dawley rats

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ANTI-INFLAMMATORY PROPERTIES

Antinociceptive and Anti-inflammatory activities of the ethanol extract of Annona Muricata L. leaves in Animal Models

This study shows that sourop leaves have tremendous pain-relieving and anti-inflammatory or anti-swelling properties. View this paper

ANALYSES MADE AT THE LABORATORIO FIM DE NUTRICION, HAVANA, CUBA.

OTHER RESEARCH PAPER

'Action of aetogenins on breast cancer' to 1. vii. Selective Action of Acetogenin Mitochondrial Complex I Inhibitors

'Annonacin induces cell cycle-dependent growth arrest and apoptosis in estrogen' to 1. v. Annonacin induces cell cycle-dependent growth arrest and apoptosis in estrogen receptor- _-related pathways in MCF-7 cells.

'Anti-Inflammatory quality of annona muricata' to 6. i. Antinociceptive and Anti-inflammatory activities of the ethanol extract of Annona Muricata L. leaves in Animal Models

'Quantitative Assessment of the Relative Antineoplastic Muricata Linn.' to 1. viii. Quantitative Assessment of the Relative Antineoplastic Potential of the n-butanolic Leaf Extract of Annona Muricata Linn. in Normal and Immortalized Human Cell Lines
'Chemopreventive Potential of Annona Muricata L Leaves' to 1. vi. Chemopreventive Potential of Annona Muricata L Leaves on Chemically-Induced Skin Papillomagenesis in Mice

'Purdue Paper' to 1. i. Tumor cell growth inhibition by several Annonaceous acetogenins in an in vitro disk diffusion assay
'Diabetes Study' to 4. 1. Anti Hyperglycemic Activities of Annona Muricata (Linn)

The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells' to 1. iii. The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells

'Graviola' to 1. iv. Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism

'Hypotensive' to 5. i. Possible mechanisms of action of the hypotensive effect of Annona muricata (soursop) in normotensive Sprague–Dawley rats.